ApexBio/DiscoveryProbe™ GPCR/G protein-related Compounds Panel/5mg/well/L1009
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¥103200.00
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51600.00
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3392242852
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4000-520-616
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商品介绍
Related Products
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Molarity CalculatorDilution Calculator
| DiscoveryProbe™ GPCR/G protein-related Compounds Panel |
Sample solution is provided at 25 µL, 10mM.
Click and Customize the Panelwith your own choices of compounds/size/quantities/chemical forms etc.
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| Catalog No. | Product Name | Summary | Targets | CAS Number | Smiles | |
| A8454 | Istradefylline (KW-6002) | Selective A2A receptor antagonist | GPCR/G protein|Adenosine Receptor | 155270-99-8 | CCN1C2=C(C(=O)N(C1=O)CC)N(C(=N2)C=CC3=CC(=C(C=C3)OC)OC)C | |
| B1007 | AVE 0991 | Agonist of angiotensin-(1-7) receptor | GPCR/G protein|Angiotensin Receptor | 304462-19-9 | CCNC(=O)NS(=O)(=O)C1=C(C=C(S1)CC(C)C)C2=CC=C(C=C2)CN3C(=C(N=C3C4=CC=CC=C4)OC)C=O | |
| A1435 | CP-945598 HCl | CB1 antagonist,selective and high affinity | GPCR/G protein|Cannabinoid Receptor | 686347-12-6 | CCNC1(CCN(CC1)C2=NC=NC3=C2N=C(N3C4=CC=C(C=C4)Cl)C5=CC=CC=C5Cl)C(=O)N.Cl | |
| A5827 | AM1241 | Cannabinoid CB2 receptor agonist,potent and selective | GPCR/G protein|Cannabinoid Receptor | 444912-48-5 | CN1CCCCC1CN2C=C(C3=CC=CC=C32)C(=O)C4=C(C=CC(=C4)[N+](=O)[O-])I | |
| A2025 | Plerixafor (AMD3100) | CXCR4 antagonist; CXCR7 agonist | GPCR/G protein|CXCR | 110078-46-1 | C1CNCCNCCCN(CCNC1)CC2=CC=C(C=C2)CN3CCCNCCNCCCNCC3 | |
| A3802 | SCH 527123 | CXCR1 and CXCR2 receptors antagonist | GPCR/G protein|CXCR | 473727-83-2 | CCC(C1=CC=C(O1)C)NC2=C(C(=O)C2=O)NC3=CC=CC(=C3O)C(=O)N(C)C | |
| B1633 | CTEP (RO4956371) | MGlu5 inhibitor | GPCR/G protein|mGluR | 871362-31-1 | CC1=C(N=C(N1C2=CC=C(C=C2)OC(F)(F)F)C)C#CC3=CC(=NC=C3)Cl | |
| A3616 | MK-4305 | OX1/OX2 atagonist,potent and selective | GPCR/G protein|OX Receptor | 1030377-33-3 | CC1CCN(CCN1C(=O)C2=C(C=CC(=C2)C)N3N=CC=N3)C4=NC5=C(O4)C=CC(=C5)Cl | |
| B2166 | Ticagrelor | P2Y12 receptor antagonist | GPCR/G protein|P2Y Receptor | 274693-27-5 | CCCSC1=NC2=C(C(=N1)NC3CC3C4=CC(=C(C=C4)F)F)N=NN2C5CC(C(C5O)O)OCCO | |
| Download the GPCR/G protein-related Compounds Panel - XLSXDownload the GPCR/G protein-related Compounds Panel - SDF | ||||||
Related Biological Data
Related Biological Data
" to show IC50- Available in stock with overnight delivery and free shipping over $500
- Cost-effective and competitive price to save your findings
- Potent, selective and cell-permeable in inhibiting or activating target molecules
- Diverse in chemical structure and route of administration (oral/i.m/i.v injection etc.)
- Detailed files describing potency, selectivity and applications etc.
- Supported by published data from top peer-reviewed journals
- Guaranteed high quality with NMR and HPLC validation
| Solubility | Soluble in DMSO | Storage | Desiccate at -20°C |
| Packaging | 96 well plate | Form | Powder |
| General tips | For obtaining a higher solubility , please warm the tube at 37°C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20°C for several months. | ||
| Shipping Condition | Evaluation sample solution : ship with blue iceAll other available size:ship with RT , or blue ice upon request | ||
A wide range of well-characterized bioactive molecules that covers various targets related to GPCR, including adenosine receptor, adrenergic receptor and CXCR etc. Facilitate your research towards the insights of cancer, neurological disorders and heart diseases etc. Applicable in cellular assays, animal models and drug screenings etc.
1. Wettschureck N, Offermanns S. Mammalian G proteins and their cell typespecific functions. Physiol Rev. 2005 Oct;85(4):1159-204.Abstract G protein-mediated signaling is employed by virtually all cells in the mammalian organism and is centrally involved in diverse physiological functions such as perception of sensory information, modulation of synaptic transmission, hormone release and actions, regulation of cell contraction and migration, or cell growth and differentiation. In this review, some of the functions of heterotrimeric G proteins in defined cells and tissues are described.
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APExBIO（APExBIO Technology LLC）总部位于美国休斯顿，是一家自主研发生产、致力于为生命科学研究提供高性能产品和优质服务的供应商。公司现阶段涵盖丰富的产品线，主要包括：1. 10000 多种小分子抑制剂/激动剂——用于肿瘤、免疫、神经等生物医药各研究领域。2. 40 余个高通量化合物库——药物筛选最佳工具。3. 分子生物学产品——PCR、逆转录、qPCR、克隆、高通量 DNA 文库构建等试剂和试剂盒，公司对相关酶进行改造，使其稳定性、催化活性等有极大的提升。4. 体外转录——公司拥有国内独家mRNA体外转录合成平台，提供优质的修饰核苷酸、转录酶等各种合成原料，并可提供mRNA订制服务。5. Cy 染料、生物素——高纯度、种类丰富的 Cy 染料和生物素可用于蛋白检测、纯化等研究。6. 免疫学产品——各类细胞器染料及靶标信号放大的链霉亲和素系列和TSA系列。7. 试剂盒——高性能的 MTT、CCK-8、EdU 细胞增殖与毒性检测 Kit 和 Annexin V、Caspase 凋亡检测 Kit。8. 蛋白研究——蛋白提取抑制剂 cocktail、磷酸化蛋白研究新工具 phosbind。9. 组学服务——提供微生物多样性、转录组学等高通量测序服务。
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