ApexBio/发现探针™ 免疫学/炎症相关化合物面板/5mg/well/L1010
市场价：
¥45400.00
美元价：
22700.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Related Products
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- MLN120B
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| DiscoveryProbe™ Immunology/Inflammation-related Compounds Panel |
Sample solution is provided at 25 µL, 10mM.
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| Catalog No. | Product Name | Summary | Targets | CAS Number | Smiles | |
| A3850 | TAK-242 | TLR 4 signaling inhibitor | Immunology/Inflammation|TLR | 243984-11-4 | CCOC(=O)C1=CCCCC1S(=O)(=O)NC2=C(C=C(C=C2)F)Cl | |
| A3248 | BMS-345541 | IKK inhibitor,highly selective | NF-κB|IκB/IKK | 547757-23-3 | CC1=CC2=C(C=C1)N=C(C3=NC=C(N23)C)NCCN.Cl | |
| A3628 | MLN120B | IκB Kinase β Inhibitor | NF-κB|IκB/IKK | 783348-36-7 | CC1=C(C=CC=N1)C(=O)NC2=C3C(=CC(=C2OC)Cl)C4=C(N3)C=NC=C4 | |
| B1585 | SC-514 | ATP-competitive IKK-2 inhibitor, orally active | NF-κB|IκB/IKK | 354812-17-2 | C1=CSC=C1C2=CC(=C(S2)C(=O)N)N | |
| B3033 | Bay 11-7085 | NK-κB activation inhibitor | NF-κB|IκB/IKK | 196309-76-9 | CC(C)(C)C1=CC=C(C=C1)S(=O)(=O)C=CC#N | |
| N1855 | Andrographolide | NF-κB signaling Inhibitor | NF-κB|IκB/IKK | 5508-58-7 | CC12CCC(C(C1CCC(=C)C2CC=C3C(COC3=O)O)(C)CO)O | |
| A3891 | Triptolide | IL-2/MMP-3/MMP7/MMP19 inhibitor | NF-κB|NF-κB | 38748-32-2 | CC(C)C12C(O1)C3C4(O3)C5(CCC6=C(C5CC7C4(C2O)O7)COC6=O)C | |
| A4217 | QNZ (EVP4593) | Potent NF-κB inhibitor | NF-κB|NF-κB | 545380-34-5 | C1=CC=C(C=C1)OC2=CC=C(C=C2)CCNC3=NC=NC4=C3C=C(C=C4)N | |
| Download the Immunology/Inflammation-related Compounds Panel - XLSXDownload the Immunology/Inflammation-related Compounds Panel - SDF | ||||||
" to show IC50- Available in stock with overnight delivery and free shipping over $500
- Cost-effective and competitive price to save your findings
- Potent, selective and cell-permeable in inhibiting or activating target molecules
- Diverse in chemical structure and route of administration (oral/i.m/i.v injection etc.)
- Detailed files describing potency, selectivity and applications etc.
- Supported by published data from top peer-reviewed journals
- Guaranteed high quality with NMR and HPLC validation
| Solubility | Soluble in DMSO | Storage | Desiccate at -20°C |
| Packaging | 96 well plate | Form | Powder |
| General tips | For obtaining a higher solubility , please warm the tube at 37°C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20°C for several months. | ||
| Shipping Condition | Evaluation sample solution : ship with blue iceAll other available size:ship with RT , or blue ice upon request | ||
A wide range of well-characterized bioactive molecules that covers various targets related to immunology/inflammation, including TLR, PLA2 and NF-κB etc. Facilitate your research towards the insights of cancer, inflammatory and autoimmune diseases etc. Applicable in cellular assays, animal models and drug screenings etc.
1. Kawai T, Akira S. Toll-like receptors and their crosstalk with other innatereceptors in infection and immunity. Immunity. 2011 May 27;34(5):637-50.Abstract TLR(Toll-like receptor)-mediated recognition of components derived from a wide range of pathogens and their role in the subsequent initiation of innate immune responses is widely accepted; however, the recent discovery of non-TLR PRRs(pattern recognition receptors), such as C-type lectin receptors, NOD-like receptors, and RIG-I-like receptors, suggests that many aspects of innate immunity are more sophisticated and complex. In this review, we will focus on the role played by TLRs in mounting protective immune responses against infection and their crosstalk with other PRRs with respect to pathogen recognition.
品牌介绍
APExBIO（APExBIO Technology LLC）总部位于美国休斯顿，是一家自主研发生产、致力于为生命科学研究提供高性能产品和优质服务的供应商。公司现阶段涵盖丰富的产品线，主要包括：1. 10000 多种小分子抑制剂/激动剂——用于肿瘤、免疫、神经等生物医药各研究领域。2. 40 余个高通量化合物库——药物筛选最佳工具。3. 分子生物学产品——PCR、逆转录、qPCR、克隆、高通量 DNA 文库构建等试剂和试剂盒，公司对相关酶进行改造，使其稳定性、催化活性等有极大的提升。4. 体外转录——公司拥有国内独家mRNA体外转录合成平台，提供优质的修饰核苷酸、转录酶等各种合成原料，并可提供mRNA订制服务。5. Cy 染料、生物素——高纯度、种类丰富的 Cy 染料和生物素可用于蛋白检测、纯化等研究。6. 免疫学产品——各类细胞器染料及靶标信号放大的链霉亲和素系列和TSA系列。7. 试剂盒——高性能的 MTT、CCK-8、EdU 细胞增殖与毒性检测 Kit 和 Annexin V、Caspase 凋亡检测 Kit。8. 蛋白研究——蛋白提取抑制剂 cocktail、磷酸化蛋白研究新工具 phosbind。9. 组学服务——提供微生物多样性、转录组学等高通量测序服务。
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